Michael addition of carbonyl compounds to nitroolefins under the catalysis of new pyrrolidine-based bifunctional organocatalysts

Author:

Castán A.12345,Badorrey R.12345,Gálvez J. A.12345,López-Ram-de-Víu P.12345,Díaz-de-Villegas M. D.12345ORCID

Affiliation:

1. Instituto de Síntesis Química y Catálisis Homogénea (ISQCH)

2. CSIC – Universidad de Zaragoza

3. Departamento de Química Orgánica

4. E-50009 Zaragoza

5. Spain

Abstract

Novel bifunctional pyrrolidine-based organocatalysts applicable for the asymmetric Michael addition of aldehydes and ketones to nitroolefins have been developed.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference50 articles.

1. Total synthesis of natural and pharmaceutical products powered by organocatalytic reactions

2. A. Ricci , Asymmetric Organocatalysis at the Service of Medicinal Chemistry , ISRN Organic Chemistry , 2014 , p. 531695

3. Applications of asymmetric organocatalysis in medicinal chemistry

4. P. G. Bulger , Applications of Organocatalyzed Asymmetric Synthesis , in Comprehensive Chirality, Volume 9: Industrial Applications of Asymmetric Synthesis , ed. D. Huges , Editors-in-Chief: A. M. Carreira and H. Yamamoto , Elsevier Science , 2012 , pp. 228–252

5. Comprehensive Enantioselective Organocatalysis: Catalysts, Reactions, and Applications, three-volume set , ed. P. I. Dalko , Wiley-VCH , Weinheim, Germany , 2013

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