Synthesis of 4-substituted oxazolo[4,5-c]quinolines by direct reaction at the C-4 position of oxazoles

Author:

Akula Mahesh1234,Thigulla Yadagiri1234,Davis Connor5678,Jha Mukund5678,Bhattacharya Anupam1234

Affiliation:

1. Department of Chemistry

2. Birla Institute of Technology and Science-Pilani (Hyderabad Campus)

3. Hyderabad-500078

4. India

5. Department of Biology and Chemistry

6. Nipissing University

7. North Bay

8. Canada P1B 8L7

Abstract

Cu(TFA)2 catalysed synthesis of 4-arylsubstituted oxazolo[4,5-c]quinolines/[1,8] naphthyridines has been described via a modified Pictet–Spengler method, without prefunctionalization of the unreactive 4th position of oxazoles.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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