Preparation of labeled aromatic amino acids via late-stage 18F-fluorination of chiral nickel and copper complexes

Author:

Craig Austin12345,Kolks Niklas12345,Urusova Elizaveta A.12345,Zischler Johannes12345,Brugger Melanie12345,Endepols Heike12345ORCID,Neumaier Bernd12345ORCID,Zlatopolskiy Boris D.12345ORCID

Affiliation:

1. Forschungszentrum Jülich GmbH

2. Institute of Neuroscience and Medicine

3. INM-5 Nuclear Chemistry

4. 52425 Jülich

5. Germany

Abstract

A practical procedure for the preparation of 18F-labeled aromatic amino acids via Cu-mediated radiofluorination of chiral Ni/Cu-BPX complexes is reported.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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