Development of novel small peptide ligands for antibody purification-Reference-Cited by-同舟云学术

Development of novel small peptide ligands for antibody purification

Published:2015 Issue:82 Volume:5 Page:67093-67101
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Wei Yuping¹²³⁴⁵,Xu Jiandong¹²³⁴⁵,Zhang Liang¹²³⁴⁵,Fu Yankai¹²³⁴⁵,Xu Xia¹²³⁴⁵

Affiliation:

1. State

2. Key Laboratory of Biochemical Engineering

3. Institute of Process Engineering

4. Chinese Academy of Sciences

5. Beijing 100190

Abstract

Small peptide ligands which were designed based on the interactions with human immunoglobulin G (IgG) using the molecular simulations, can offer a potential alternative for mAb purification with elution condition at pH 9 and pH 3.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA07829F

Reference44 articles.

1. Purification of antibodies by affinity chromatography

2. Therapeutic antibodies: successes, limitations and hopes for the future

3. Advances in the production and downstream processing of antibodies

4. Future of antibody purification

5. Capture of human monoclonal antibodies from cell culture supernatant by ion exchange media exhibiting high charge density

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