Chemical synthesis of the tumor-associated globo H antigen
Author:
Affiliation:
1. Department of Chemistry
2. Wayne State University
3. Detroit
4. USA
Abstract
A convergent synthesis of Globo H antigen based on glycosylation reactions using thioglycoside and trichloroacetimidate glycosyl donors.
Funder
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA00759C
Reference37 articles.
1. Augmenting the immunogenicity of carbohydrate tumor antigens
2. Immunization of metastatic breast cancer patients with a fully synthetic globo H conjugate: A phase I trial
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