Rapid and specific detection of intact viral particles using functionalized microslit silicon membranes as a fouling-based sensor

Author:

Klaczko Michael E.1ORCID,Lucas Kilean2,Salminen Alec T.2,McCloskey Molly C.2,Ozgurun Baturay2ORCID,Ward Brian M.3ORCID,Flax Jonathan4,McGrath James L.2ORCID

Affiliation:

1. Department of Chemistry, University of Rochester, Rochester, NY, 14627 USA

2. Department of Biomedical Engineering, University of Rochester, Rochester, NY, 14627 USA

3. Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, NY, 14642 USA

4. Department of Urology, University of Rochester Medical Center, Rochester, NY, 14642 USA

Abstract

Developing a POC sensor for viral particles which requires both size and affinity for a positive test and uses a hand pipette injection for power. Achieved by applying a novel principle of fouling-based detection on ultrathin silicon-based membranes.

Funder

National Science Foundation

Empire State Development's Division of Science, Technology and Innovation

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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