A dendronized heparin–gadolinium polymer self-assembled into a nanoscale system as a potential magnetic resonance imaging contrast agent

Author:

Guo Chunhua12345,Sun Ling67385,She Wenchuan12345,Li Ning12345,Jiang Lei12345,Luo Kui12345,Gong Qiyong67385,Gu Zhongwei12345

Affiliation:

1. National Engineering Research Center for Biomaterials

2. 29 Wangjiang Road

3. Sichuan University

4. Chengdu 610064

5. China

6. Department of Radiology

7. West China Hospital

8. Chengdu 610041

Abstract

An amphiphilic dendronized heparin–gadolinium conjugate self-assembles into a nanoscale system by a combination of the features of the nanoparticle, dendrimer and heparin. The nanoscale system demonstrates great potential as an efficient and safe MRI contrast agent.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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