A highly sensitive and selective fluorescent biosensor for breast cancer derived exosomes using click reaction of azide–CD63 aptamer and alkyne-polymer dots-Reference-Cited by-同舟云学术

A highly sensitive and selective fluorescent biosensor for breast cancer derived exosomes using click reaction of azide–CD63 aptamer and alkyne-polymer dots

Published:2024 Issue:17 Volume:16 Page:2751-2759
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Ma Dumei¹,Luo Yiting¹,Zhang Xiaoya¹,Xie Zehu¹,Yan Yinghua¹^ORCID,Ding Chuan-Fan¹

Affiliation:

1. Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Institute of Mass Spectrometry, School of Material Science and Chemical Engineering, Ningbo University, Ningbo, Zhejiang 315211, China

Abstract

A fluorescence method based on Cu-triggered click reaction of azide modified CD63 aptamer and alkyne capped Pdots was developed for breast cancer derived exosome detection.

Funder

Natural Science Foundation of Zhejiang Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/AY/D4AY00146J

Reference41 articles.

1. Biological Functions and Current Advances in Isolation and Detection Strategies for Exosome Nanovesicles

2. Molecular Recognition-Based DNA Nanoassemblies on the Surfaces of Nanosized Exosomes

3. Aptamer/AuNP Biosensor for Colorimetric Profiling of Exosomal Proteins

4. Detecting Exosomes Specifically: A Multiplexed Device Based on Alternating Current Electrohydrodynamic Induced Nanoshearing

5. Aptasensor with Expanded Nucleotide Using DNA Nanotetrahedra for Electrochemical Detection of Cancerous Exosomes

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