Direct salinization of trelagliptin from solid forms by mechanochemistry and its mechanism of salt formation-Reference-Cited by-同舟云学术

Direct salinization of trelagliptin from solid forms by mechanochemistry and its mechanism of salt formation

Published:2020 Issue:47 Volume:22 Page:8256-8265
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Xu Kailin¹²³⁴,Qian Menglin¹²³⁴,Leng Jiewu⁵⁶²⁴^ORCID,Bai Jie⁷²³⁴,Li Qinglan¹²³⁴,Liu Zihong¹²³⁴,Zhong Shijuan¹²³⁴,Zhao Suqing¹²³⁴^ORCID

Affiliation:

1. School of Biomedical and Pharmaceutical Sciences

2. Guangdong University of Technology

3. Guangzhou

4. China

5. Guangdong Provincial Key Laboratory of Computer Integrated Manufacturing System

6. State Key Laboratory of Precision Electronic Manufacturing Technology and Equipment, Guangzhou

7. Analysis and Test Center

Abstract

The direct salinization of trelagliptin from solid forms by mechanochemistry was developed, which clarified that similar intermolecular interactions and any factor inducing proton transfer have a vital role in the formation of API salts.

Funder

National Natural Science Foundation of China

Science and Technology Planning Project of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CE/D0CE00984A

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