Stealth nanorods via the aqueous living crystallisation-driven self-assembly of poly(2-oxazoline)s

Author:

Finnegan John R.12345ORCID,Pilkington Emily H.12345ORCID,Alt Karen67489ORCID,Rahim Md. Arifur1011129ORCID,Kent Stephen J.131415165ORCID,Davis Thomas P.12345ORCID,Kempe Kristian12345ORCID

Affiliation:

1. ARC Centre of Excellence in Convergent Bio-Nano Science and Technology

2. Drug Delivery, Disposition and Dynamics

3. Monash Institute of Pharmaceutical Sciences

4. Monash University

5. Parkville

6. NanoTheranostics Laboratory

7. Australian Centre for Blood Diseases

8. Melbourne

9. Australia

10. School of Chemical Engineering

11. University of New South Wales (UNSW)

12. Sydney

13. ARC Centre of Excellence in Convergent Bio-Nano Science

14. Department of Microbiology and Immunology

15. Peter Doherty Institute for Infection and Immunity

16. The University of Melbourne

Abstract

Triggered by heating, a poly(2-alkyl-2-oxazoline) block copolymer undergoes seeded growth in water forming length tuneable nanorods. Morphology and composition combine to impart low immune cell association and promising blood circulation lifetimes.

Funder

National Health and Medical Research Council

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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