A bifunctional imidazolium-based cholesterol analog for the tracking of cellular cholesterol distributions and cholesterol–protein interactions-Reference-Cited by-同舟云学术

A bifunctional imidazolium-based cholesterol analog for the tracking of cellular cholesterol distributions and cholesterol–protein interactions

Published:2023 Issue:23 Volume:21 Page:4817-4822
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Wegner Tristan¹,Matos Anna L. L.²,Porte Karine¹^ORCID,Mehring Kira²,Pierau Marco¹,Horstmeier Hendrik²,Gerke Volker²,Glorius Frank¹^ORCID

Affiliation:

1. University of Münster, Institute of Organic Chemistry, Corrensstraße 40, Münster, Germany

2. University of Münster, Institute of Medicinal Biochemistry, Center for Molecular Biology of Inflammation, Von-Esmarch-Straße 56, Münster, Germany

Abstract

Lipid mimetics are pivotal tools for lipid biology research. Herein, a bifunctional cholesterol mimetic was designed and investigated for its potential to enable concurrent exploration of cellular cholesterol distributions and protein interactions.

Funder

Deutsche Forschungsgemeinschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D3OB00494E

Reference53 articles.

1. How Cells Handle Cholesterol

2. Cellular cholesterol trafficking and compartmentalization

3. Effect of cholesterol on the structure of a phospholipid bilayer

4. High Cholesterol/Low Cholesterol: Effects in Biological Membranes: A Review

5. Regulation of membrane protein structure and function by their lipid nano-environment

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