Antitumor effects of novel nickel–hydrazone complexes in lung cancer cells-Reference-Cited by-同舟云学术

Antitumor effects of novel nickel–hydrazone complexes in lung cancer cells

Published:2020 Issue:21 Volume:44 Page:9064-9072
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Ay Burak¹²³⁴^ORCID,Şahin Onur⁵⁶⁴,Saygıdeğer Demir Burcu⁷³⁴,Saygideger Yasemin⁷³⁴⁸⁹^ORCID,López-de-Luzuriaga José M.¹⁰¹¹¹²¹³¹⁴^ORCID,Mahmoudi Ghodrat¹⁵¹⁶¹⁷¹⁸,Safin Damir A.¹⁹²⁰²¹²²²³^ORCID

Affiliation:

1. Department of Chemistry, Arts and Science Faculty

2. Çukurova University

3. Adana

4. Turkey

5. Sinop University, Scientific and Technological Research Application and Research Center

6. Sinop

7. Central Research Laboratory of Cukurova University (CUMERLAB)

8. Department of Pulmonary

9. Cukurova University School of Medicine

10. Departamento de Química

11. Centro de Investigación en Síntesis Química (CISQ)

12. Universidad de La Rioja

13. Complejo Científico-Tecnoloǵico

14. 26006-Logroño

15. Department of Chemistry

16. Faculty of Science, University of Maragheh

17. Maragheh

18. Iran

19. University of Tyumen

20. Perekopskaya Str. 15a

21. 625003 Tyumen

22. Russian Federation

23. West-Siberian Interregional Scientific and Educational Center

Abstract

Two novel nickel(ii) complexes [NiL^I]·CH₃CN (1·CH₃CN) and [Ni(H₂L^II)(NCS)₂]·0.5H₂O (2·0.5H₂O) were fabricated and in in vitro experiments they both showed the dose dependent cytotoxicity and killed A549 lung cancer cells via an apoptotic pathway.