Rapid GSH detection and versatile peptide/protein labelling to track cell penetration using coumarin-based probes

Author:

Xue Li12,Yu Dehao1,Sun Jing1,Guan Liangyu3,Xie Chengzhi1ORCID,Wang Luo1,Jia Yuanyuan1,Tian Junyu1,Fan Heli1,Sun Huabing1ORCID

Affiliation:

1. The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Tianjin Medical University; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin 300070, P. R. China

2. School of Pharmacy, Jinzhou Medical University, Jinzhou, Liaoning 121001, P. R. China

3. BayRay Innovation Center, Shenzhen Bay Laboratory, Shenzhen, Guangdong 518132, P. R. China

Abstract

Fluorogenic probes, reacting quantitatively and quickly with GSH monitor GSH in vitro and in vivo. Moreover, fluorescently labelling peptides or proteins using the probes affords powerful tools to investigate their cell penetrating ability.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3