Low-dose exposure to phytosynthesized gold nanoparticles combined with glutamine deprivation enhances cell death in the cancer cell line HeLa <i>via</i> oxidative stress-mediated mitochondrial dysfunction and G0/G1 cell cycle arrest-Reference-Cited by-同舟云学术

Low-dose exposure to phytosynthesized gold nanoparticles combined with glutamine deprivation enhances cell death in the cancer cell line HeLa via oxidative stress-mediated mitochondrial dysfunction and G0/G1 cell cycle arrest

Published:2022 Issue:29 Volume:14 Page:10399-10417
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Prasad Abhinav¹^ORCID,Khatua Ashapurna²,Mohanta Yugal Kishore³,Saravanan Muthupandian⁴^ORCID,Meena Ramovatar²,Ghosh Ilora¹^ORCID

Affiliation:

1. Biochemistry and Environmental Toxicology Laboratory, Lab#103, School of Environmental Sciences, Jawaharlal Nehru University, New Delhi 110067, India

2. Nanotoxicology Laboratory, Lab#312, School of Environmental Sciences, Jawaharlal Nehru University, New Delhi 110067, India

3. Department of Applied Biology, School of Biological Sciences University of Science and Technology Meghalaya, Ri-Bhoi-793101, India

4. AMR and Nanotherapeutics Laboratory, Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences (SIMATS), Chennai 600077, India

Abstract

Glutamine deprivation sensitizes cancer cells HeLa to mitochondrial inactivity and cell cycle arrest mediated cell death induction by low-dose phytosynthesized gold nanoparticles.

Funder

Department of Science and Technology, Ministry of Science and Technology, India

Indian Council of Medical Research

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NR/D2NR02150A

Reference85 articles.

1. Green nanotechnology-based tellurium nanoparticles: Exploration of their antioxidant, antibacterial, antifungal and cytotoxic potentials against cancerous and normal cells compared to potassium tellurite