Anti-cancer effects of torulene, isolated from Sporidiobolus pararoseus, on human prostate cancer LNCaP and PC-3 cells via a mitochondrial signal pathway and the down-regulation of AR expression-Reference-Cited by-同舟云学术

Anti-cancer effects of torulene, isolated from Sporidiobolus pararoseus, on human prostate cancer LNCaP and PC-3 cells via a mitochondrial signal pathway and the down-regulation of AR expression

Published:2017 Issue:5 Volume:7 Page:2466-2474
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Du Chao¹²³⁴²,Guo Yahui¹²³,Cheng Yuliang¹²³,Han Mei⁴²³,Zhang Weiguo⁴²³,Qian He¹²³⁵²

Affiliation:

1. School of Food Science and Technology

2. Jiangnan University

3. P. R. China

4. School of Biotechnology

5. National Engineering Research Center for Functional Food

Abstract

Torulene, inhibit LNCaP and PC-3 cells growth through Bcl-2/Bax mediated apoptosis and AR down-regulation.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/RA/C6RA24721K

Reference28 articles.

1. Lycopene and Apo-12'-Lycopenal Reduce Cell Proliferation and Alter Cell Cycle Progression in Human Prostate Cancer Cells

2. Lycopene Inhibits the Growth of Human Androgen-Independent Prostate Cancer Cells In Vitro and in BALB/c Nude Mice

3. Autophagy is differentially induced in prostate cancer LNCaP, DU145 and PC-3 cells via distinct splicing profiles of ATG5

4. Fenofibrate down-regulates the expressions of androgen receptor (AR) and AR target genes and induces oxidative stress in the prostate cancer cell line LNCaP

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