Synthesis of indole-derived allocolchicine congeners exhibiting pronounced anti-proliferative and apoptosis-inducing properties-Reference-Cited by-同舟云学术

Synthesis of indole-derived allocolchicine congeners exhibiting pronounced anti-proliferative and apoptosis-inducing properties

Published:2015 Issue:12 Volume:6 Page:2158-2162
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Sitnikov Nikolay S.¹²³⁴⁵,Sinzov Alexander V.¹²³⁴,Allegro Diane⁶⁷⁸,Barbier Pascale⁶⁷⁸,Combes Sebastien⁹⁶⁷⁸,Onambele Liliane Abodo¹⁰¹¹¹²,Prokop Aram¹⁰¹¹¹²,Schmalz Hans-Günther⁵¹³¹⁴¹²,Fedorov Alexey Yu.¹²³⁴

Affiliation:

1. Department of Organic Chemistry

2. Lobachevsky State University of Nizhni Novgorod

3. Nizhni Novgorod 603950

4. Russia

5. Department für Chemie

6. Aix-Marseille Université

7. Marseille

8. France

9. Laboratory of Integrative Structural and Chemical Biology, Institut Paoli-Calmettes

10. Department of Pediatric Hematology/Oncology

11. 50735 Köln

12. Germany

13. Universität zu Köln

14. Köln

Abstract

The synthesis and biological assessment of indole-based allocolchicine congeners with potent anti-proliferative and apoptosis-inducing activity are reported.

Funder

Ministry of Education and Science of the Russian Federation

Deutsche Forschungsgemeinschaft

Russian Foundation for Basic Research

Alexander von Humboldt-Stiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MD/C5MD00320B

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