Phosphine-catalyzed [3 + 2] and [4 + 2] annulation reactions of ynones with barbiturate-derived alkenes

Author:

Gao Xing1234,Li Zhen1234,Yang Wenjun1234,Liu Yang1234,Chen Wufeng1234,Zhang Cheng1234ORCID,Zheng Lufei5674,Guo Hongchao12348ORCID

Affiliation:

1. Department of Applied Chemistry

2. China Agricultural University

3. Beijing 100193

4. China

5. Institute of Quality Standards & Testing Technology for Agro-Products

6. Chinese Academy of Agricultural Sciences

7. Beijing 100081

8. Key Laboratory of Green Pesticide and Agricultural Bioengineering

Abstract

The phosphine-catalyzed [3 + 2] annulation reaction of ynones and barbiturate-derived alkenes has been developed with the assistance of a weak acid, giving functionalized spirobarbiturate-cyclopentanones.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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3. Pharmacotherapy of Essential Tremor

4. D. J. Abraham and D. P.Rotella, Burger's Medicinal Chemistry, Drug Discovery and Development, Wiley, Hoboken, 2010

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