Highly enantioselective Michael addition of diethyl malonate to chalcones catalyzed by cinchona alkaloids-derivatived bifunctional tertiary amine-thioureas bearing multiple hydrogen-bonding donors-Reference-Cited by-同舟云学术

Highly enantioselective Michael addition of diethyl malonate to chalcones catalyzed by cinchona alkaloids-derivatived bifunctional tertiary amine-thioureas bearing multiple hydrogen-bonding donors

Published:2014 Issue:20 Volume:12 Page:3163-3166
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Liu Yulong¹²³⁴,Wang Xie¹²³⁴,Wang Xiaoyun¹²³⁴,He Wei¹²³⁴

Affiliation:

1. Department of Chemistry

2. School of Pharmacy

3. Fourth Military Medical University

4. Xi'an 710032, P. R. China

Abstract

Both enantiomers of diethyl 2-(3-oxo-1,3-arylpropyl)malonate are easily prepared by a highly enantioselective Michael addition of diethyl malonate with chalcones catalyzed by cinchona alkaloids-derivatived organocatalysts.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00203B

Reference54 articles.

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4. Michael Additions of Benzotriazole-Stabilized Carbanions. A Review

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