An enantioselective strategy for the total synthesis of (S)-tylophorine via catalytic asymmetric allylation and a one-pot DMAP-promoted isocyanate formation/Lewis acid catalyzed cyclization sequence
Author:
Affiliation:
1. State Key Laboratory of Elemento-Organic Chemistry
2. Research Institute of Elemento-Organic Chemistry
3. Nankai University
4. Tianjin 300071, People's Republic of China
Abstract
A novel total synthesis of (S)-tylophorine is reported, featuring asymmetric allylation and cascade isocyanate formation and cyclization.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00200H
Reference48 articles.
1. Alkaloids of Pergularia pallida
2. Phenanthroindolizidines and Phenanthroquinolizidines: Promising Alkaloids for Anti-Cancer Therapy
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