Glial restricted precursor delivery of dendrimer N-acetylcysteine promotes migration and differentiation following transplant in mouse white matter injury model-Reference-Cited by-同舟云学术

Glial restricted precursor delivery of dendrimer N-acetylcysteine promotes migration and differentiation following transplant in mouse white matter injury model

Published:2020 Issue:30 Volume:12 Page:16063-16068
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Nemeth Christina L.¹²³⁴^ORCID,Tomlinson Sophia N.¹²³⁴^ORCID,Sharma Rishi⁵⁶⁷³⁴^ORCID,Sharma Anjali⁵⁶⁷³⁴,Kannan Sujatha¹²³⁴⁸^ORCID,Kannan Rangaramanujam M.¹²³⁴⁵^ORCID,Fatemi Ali¹²³⁴⁹^ORCID

Affiliation:

1. Moser Center for Leukodystrophies

2. Kennedy Krieger Institute

3. Baltimore

4. USA

5. Center for Nanomedicine

6. Department of Ophthalmology

7. Wilmer Eye Institute Johns Hopkins University School of Medicine

8. Anesthesiology & Critical Care Medicine

9. Department of Neurology

Abstract

Dendrimer-NAC improves the long-term engraftment of transplanted cells to the brain, suggesting targeted nanotherapeutic support may eliminate the need for overt immunosuppression or multiple invasive procedures in regenerative therapies.

Funder

National Institute of Neurological Disorders and Stroke

Eunice Kennedy Shriver National Institute of Child Health and Human Development

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NR/C9NR10804A

Reference27 articles.

1. Mesenchymal stem cell therapies in brain disease

2. Stem cell delivery of therapies for brain disorders