Toxicological implications of mitochondrial localization of CYP2E1-Reference-Cited by-同舟云学术

Toxicological implications of mitochondrial localization of CYP2E1

Published:2017 Issue:3 Volume:6 Page:273-289
ISSN:2045-452X
Container-title:Toxicology Research
language:en
Short-container-title:Toxicol. Res.

Author:

Hartman Jessica H.¹²³⁴^ORCID,Miller Grover P.⁵⁶⁷⁴,Meyer Joel N.¹²³⁴

Affiliation:

1. Nicholas School of the Environment

2. Duke University

3. Durham

4. USA

5. Biochemistry and Molecular Biology

6. University of Arkansas for Medical Sciences

7. Little Rock

Abstract

This review discusses links between mitochondria-localized cytochrome P450 2E1 (CYP2E1) and toxicity, particularly mitochondrial dysfunction, and poses open questions in this emerging field.

Funder

National Institute of Environmental Health Sciences

U.S. National Library of Medicine

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://pubs.rsc.org/en/content/articlepdf/2017/TX/C7TX00020K

Reference160 articles.

1. Oxidative and reductive metabolism by cytochrome P450 2E1

2. Cytochrome P450 2E1: its clinical and toxicological role

3. The alcohol-inducible form of cytochrome P450 (CYP2E1): Role in toxicology and regulation of expression

4. Cytochrome P-4502E1: its physiological and pathological role

5. Advances in the interpretation and prediction of CYP2E1 metabolism from a biochemical perspective

Cited by 22 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. CYP2E1 mediated advanced oxidation protein products exacerbate acetaminophen induced drug-derived liver injury in vitro and in vivo;European Journal of Pharmaceutical Sciences;2024-09

2. The Wnt/β-catenin signaling pathway plays a role in drug-induced liver injury by regulating cytochrome P450 2E1 expression;Toxicological Research;2023-04-14

3. An Updated Overview of the Role of CYP450 during Xenobiotic Metabolization in Regulating the Acute Myeloid Leukemia Microenvironment;International Journal of Molecular Sciences;2023-03-23

4. Ethanol Metabolism and Melanoma;Cancers;2023-02-16

5. Time to Change: A Systems Pharmacology Approach to Disentangle Mechanisms of Drug-Induced Mitochondrial Toxicity;Pharmacological Reviews;2023-01-10