Photocatalytic redox-neutral arylation of cyclopropanols with cyanoarenes via radical-mediated C–C and C–CN bond cleavage

Author:

Tong Yue1,Hao Na1,Zhang Long1,Wei Jun1,Zhang Zhijie1,Fu Qiang1ORCID,Yi Dong1ORCID,Mou Yao2,Wang Jun1,Pan Xianchao1,Yang Lin1,Wei Siping1ORCID,Zhong Lei3,Lu Ji1ORCID

Affiliation:

1. School of Pharmacy, Southwest Medical University, Luzhou 646000, China

2. Department of Pharmacy, the Affiliated Hospital of Southwest Medical University, Luzhou 646000, China

3. Department of Pharmacy, Personalized Drug Therapy Key Laboratory of Sichuan Province Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610072, China

Abstract

This work describes a photocatalytic redox-neutral arylation of cyclopropanols with cyanoarenes via radical-mediated C–C and C–CN bond cleavage to afford various β-arylated ketones.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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