Non-invasive and label-free identification of human natural killer cell subclasses by biophysical single-cell features in microfluidic flow-Reference-Cited by-同舟云学术

Non-invasive and label-free identification of human natural killer cell subclasses by biophysical single-cell features in microfluidic flow

Published:2021 Issue:21 Volume:21 Page:4144-4154
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Dannhauser David¹^ORCID,Rossi Domenico²^ORCID,Palatucci Anna Teresa³,Rubino Valentina⁴,Carriero Flavia⁴,Ruggiero Giuseppina⁴,Ripaldi Mimmo⁵,Toriello Mario⁵,Maisto Giovanna⁵,Netti Paolo Antonio¹²,Terrazzano Giuseppe³,Causa Filippo¹^ORCID

Affiliation:

1. Interdisciplinary Research Centre on Biomaterials (CRIB) and Dipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale, Università degli Studi di Napoli “Federico II”, Piazzale Tecchio 80, 80125 Naples, Italy

2. Center for Advanced Biomaterials for Healthcare@CRIB, Istituto Italiano di Tecnologia, Largo Barsanti e Matteucci 53, 80125 Naples, Italy

3. Dipartimento di Scienze (DiS), Università della Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy

4. Dipartimento di Scienze Mediche Traslazionali, Università degli Studi di Napoli “Federico II”, Naples, Italy

5. Dipartimento Oncologia AORN Santobono Pausilipon Hospital, Via Posillipo, 226, 80123, Naples, Italy

Abstract

A label-free light scattering analysis together with a machine learning approach provide cellular distinction of immature regulatory NK CD56bright from mature cytotoxic NK CD56dim.

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/LC/D1LC00651G

Reference75 articles.

1. Targeting natural killer cells and natural killer T cells in cancer

2. Gliadin Regulates the NK-Dendritic Cell Cross-Talk by HLA-E Surface Stabilization

3. Natural killer expansion, human leukocyte antigens-E expression and CD14+CD56+monocytes in a myelodysplastic syndrome patient

4. Human NK cells: surface receptors, inhibitory checkpoints, and translational applications

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