Evaluating nanoparticle localisation in glioblastoma multicellular tumour spheroids by surface enhanced Raman scattering

Author:

McCabe Samantha M.12ORCID,Wallace Gregory Q.1ORCID,Sloan-Dennison Sian1ORCID,Tipping William J.1ORCID,Shand Neil C.2,Graham Duncan1ORCID,Boyd Marie3,Faulds Karen1ORCID

Affiliation:

1. Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK

2. The Defence Science and Technology Laboratory (Dstl), Porton Down, Salisbury, SP4 0JQ, UK

3. Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, 161 Cathedral Street, Glasgow, G4 0RE, UK

Abstract

Combining SERS and immunohistochemistry provides greater insight into how AuNPs distribute in in vitro 3D MTS models.

Funder

University of Strathclyde

Defence Science and Technology Laboratory

Biotechnology and Biological Sciences Research Council

Medical Research Council

Leverhulme Trust

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Reference42 articles.

1. Cancer Research UK, https://www.cancerresearchuk.org/health-professional/cancer-statistics-for-the-uk

2. Cancer Research UK, https://www.cancerresearchuk.org/health-professional/cancer-statistics/statistics-by-cancer-type/brain-other-cns-and-intracranial-tumours

3. Drug Resistance and the Solid Tumor Microenvironment

4. Characterization of multicellular breast tumor spheroids using image data-driven biophysical mathematical modeling

5. Multicellular spheroids: a three‐dimensionalin vitroculture system to study tumour biology

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