Overview of the structure, side effects, and activity assays of <scp>l</scp>-asparaginase as a therapy drug of acute lymphoblastic leukemia-Reference-Cited by-同舟云学术

Overview of the structure, side effects, and activity assays of l-asparaginase as a therapy drug of acute lymphoblastic leukemia

Published:2022 Issue:2 Volume:13 Page:117-128
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Wang Nanxiang¹,Ji Wenhui¹,Wang Lan¹,Wu Wanxia¹,Zhang Wei¹,Wu Qiong¹^ORCID,Du Wei¹,Bai Hua²,Peng Bo²,Ma Bo³,Li Lin¹^ORCID

Affiliation:

1. Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University, Nanjing, 211800, China

2. Frontiers Science Center for Flexible Electronics, Xi'an Institute of Flexible Electronics (IFE) and Xi'an Institute of Biomedical Materials & Engineering, Northwestern Polytechnical University, Xi'an, 710072, China

3. School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, 211800, China

Abstract

We summarized its structure and mechanism in detail, reviewed the detection approaches, and prospected the development of future detection assays.

Funder

Key Technologies Research and Development Program

Fundamental Research Funds for the Central Universities

National Natural Science Foundation of China

ShanXi Science and Technology Department

Northwestern Polytechnical University

Natural Science Foundation of Ningbo

Shanxi Provincial Key Research and Development Project

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/MD/D1MD00344E

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2. MLL-Rearranged Acute Leukemia with t(4;11)(q21;q23)—Current Treatment Options. Is There a Role for CAR-T Cell Therapy?

3. REGRESSION OF TRANSPLANTED LYMPHOMAS INDUCED IN VIVO BY MEANS OF NORMAL GUINEA PIG SERUM

4. EVIDENCE THAT THE L-ASPARAGINASE OF GUINEA PIG SERUM IS RESPONSIBLE FOR ITS ANTILYMPHOMA EFFECTS

5. Factors which may influence the effectiveness of L-asparaginases as tumor inhibitors

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