Gold nanoparticle probes for colorimetric detection of plasma galectin-3: a simple and rapid approach

Author:

António Maria1ORCID,Lima Tânia23,Ferreira Rita45,Fardilha Margarida2,Bastos José Mesquita26,Vitorino Rui257,Daniel-da-Silva Ana L.1ORCID

Affiliation:

1. CICECO-Aveiro Institute of Materials, Department of Chemistry, University, of Aveiro, Aveiro 3810-193, Portugal

2. iBiMED-Institute of Biomedicine, Department of Medical Sciences, University of Aveiro, Aveiro, 3810-193, Portugal

3. Cancer Biology and Epigenetics Group, Research Center of Portuguese Oncology Institute of Porto (GEBC CI-IPOP) & Porto Comprehensive Cancer Center (P.CCC), Porto 4200-072, Portugal

4. QOPNA, Department of Chemistry, University of Aveiro, Aveiro, 3810-193, Portugal

5. LAQV-REQUIMTE, Chemistry Department, University of Aveiro, Aveiro, 3810-193, Portugal

6. Cardiology Department, Hospital Infante D. Pedro, Centro Hospitalar do Baixo Vouga, Aveiro, Portugal

7. UnIC@RISE, Department of Surgery and Physiology, Cardiovascular R&D Center, Faculty of Medicine of the University of Porto, Alameda Professor Hernâni Monteiro, Porto 4200-319, Portugal

Abstract

First colorimetric and low-cost approach for detecting and quantifying galectin-3 using gold nanoparticles (AuNPs) bioconjugated with Gal-3 antibody.

Funder

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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