Functional polymeric dialdehyde dextrin network capped mesoporous silica nanoparticles for pH/GSH dual-controlled drug release-Reference-Cited by-同舟云学术

Functional polymeric dialdehyde dextrin network capped mesoporous silica nanoparticles for pH/GSH dual-controlled drug release

Published:2018 Issue:37 Volume:8 Page:20862-20871
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Chen Chao¹²³⁴⁵^ORCID,Sun Wen¹²³⁴⁵^ORCID,Yao Wenji¹²³⁴⁵,Wang Yibing¹²³⁴⁵,Ying Hanjie⁶⁷⁸⁹¹⁰^ORCID,Wang Ping¹²³⁴⁵

Affiliation:

1. State Key Laboratory of Bioreactor Engineering

2. Shanghai Collaborative Innovation Center for Biomanufacturing

3. Biomedical Nanotechnology Center

4. School of Biotechnology

5. East China University of Science and Technology

6. State Key Laboratory of Materials-Oriented Chemical Engineering

7. College of Biotechnology and Pharmaceutical Engineering

8. Nanjing Tech University

9. Nanjing 211816

10. People's Republic of China

Abstract

A smart pH/GSH dual-responsive drug delivery system by using DAD as a “gatekeeper polymer” to end-cap MSNs via pH-sensitive Schiff bond, whereas DAD polymer shell were cross-linked by GSH-sensitive disulfide bond.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA03163K

Reference53 articles.

1. Redox-responsive mesoporous selenium delivery of doxorubicin targets MCF-7 cells and synergistically enhances its anti-tumor activity

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5. Nanonization strategies for poorly water-soluble drugs

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