Electrogenerated chemiluminescence of a Ru(bpy)32+/arginine system: a specific and sensitive detection of acetaminophen

Author:

Xiao Yi12ORCID,Wang Guofang1,Yi Haomin1,Chen Suhua3,Wu Qinyu1,Zhang Siyi1,Deng Kexin1,Zhang Simeng1,Shi Zi-Qi4,Yang Xiaoping1ORCID

Affiliation:

1. Key Laboratory of Study and Discovery of Small Targeted Molecules of Hunan Province, Department of Pharmacy, School of Medicine, Hunan Normal University, Changsha 410013, Hunan, China

2. John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, MA 02138, USA

3. Hunan Provincial Maternal and Child Health Care Hospital, Changsha 410008, Hunan, China

4. Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing 210028, Jiangsu, China

Abstract

We use arginine as an alternative co-reactant for Ru(bpy)32+ by taking advantage of its low cost, non-toxicity, and biocompatibility. It is promising to expand the scope of the Ru(bpy)32+/Arg system and move forward their applications in bioassays.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hunan Province

Key Project of Research and Development Plan of Hunan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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