Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties-Reference-Cited by-同舟云学术

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

Published:2020 Issue:22 Volume:44 Page:9202-9212
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Shanker Arun K.¹²³^ORCID,Bhanu Divya¹²³⁴⁵,Alluri Anjani⁶⁷⁸³,Gupta Samriddhi⁹¹⁰¹¹³

Affiliation:

1. ICAR – Central Research Institute for Dryland Agriculture, Santoshnagar

2. Hyderabad – 500059

3. India

4. Centre for Plant Molecular Biology

5. Osmania University

6. Advanced Post Graduate Centre

7. Acharya N. G. Ranga Agricultural University

8. Guntur

9. Department of Biochemistry

10. School of Life Sciences

11. University of Hyderabad

Abstract

SARS-CoV-2 3CLpro shows homology in binding to an aza-peptide epoxide (APE) known for the irreversible inhibition of main peptidase in SARS-CoV.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/NJ/D0NJ00974A

Reference45 articles.

1. World Health Organization (WHO), 2004, accessed 11 Feb 2020, https://www.who.int/csr/don/2004_05_18a/en/

2. SARS and MERS: recent insights into emerging coronaviruses

3. Middle East respiratory syndrome coronavirus (MERS-CoV) causes transient lower respiratory tract infection in rhesus macaques

4. World Health Organization (WHO). Coronavirus. Geneva: WHO, 2020, accessed 4 Feb 2020, available from: https://www.who.int/health-topics/coronavirus

5. World Health Organization (WHO), 2020, accessed 27 April 2020, https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200423-sitrep-94-covid-19.pdf?sfvrsn=b8304bf0_4

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