Synergistic action of 6-gingerol as an adjuvant to colistin for susceptibility enhancement in multidrug-resistant <i>Klebsiella pneumoniae</i> isolates-Reference-Cited by-同舟云学术

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Synergistic action of 6-gingerol as an adjuvant to colistin for susceptibility enhancement in multidrug-resistant Klebsiella pneumoniae isolates

Published:2024 Issue:11 Volume:14 Page:7779-7785
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sahoo Maheswata¹,Behera Dibyajyoti Uttameswar¹,Sahoo Rajesh Kumar¹,Sahoo Saubhagini¹,Dey Suchanda¹,Subudhi Enketeswara¹^ORCID

Affiliation:

1. Centre for Biotechnology, Siksha ‘O’ Anusandhan (Deemed to be University), Kalinga Nagar, Ghatikia, Bhubaneswar 751003, Odisha, India

Abstract

The rapid emergence of MDR Klebsiella pneumoniae demands alternative therapy. 6-Gingerol is a natural phytocompound that has synergistic and bactericidal effects against MDR-KP isolates. It exhibited promising EPI activity to stop colistin efflux.

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D3RA07835C

Reference35 articles.

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Antimicrobial Resistance: Implications and Costs

3. Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects

4. Emerging Strategies to Combat ESKAPE Pathogens in the Era of Antimicrobial Resistance: A Review

5. Population genomics of Klebsiella pneumoniae

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