Pathological levels of glucosylceramide change the biophysical properties of artificial and cell membranes-Reference-Cited by-同舟云学术

Pathological levels of glucosylceramide change the biophysical properties of artificial and cell membranes

Published:2017 Issue:1 Volume:19 Page:340-346
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Varela Ana R. P.¹²³⁴⁵,Ventura Ana E.¹²³⁴⁵,Carreira Ana C.¹²³⁴⁵,Fedorov Aleksander⁶⁷³⁸⁵,Futerman Anthony H.⁹¹⁰¹¹¹²,Prieto Manuel⁶⁷³⁸⁵,Silva Liana C.¹²³⁴⁵^ORCID

Affiliation:

1. iMed.ULisboa – Research Institute for Medicines

2. Faculdade de Farmácia

3. Universidade de Lisboa

4. 1649-003 Lisboa

5. Portugal

6. Centro de Química-Física Molecular and Institute of Nanoscience and Nanotechnology

7. Instituto Superior Técnico

8. 1049-001 Lisboa

9. Department of Biomolecular Sciences

10. Weizmann Institute of Science

11. Rehovot 76100

12. Israel

Abstract

Accumulation of glucosylceramide decreases membrane fluidity in artificial membranes and in cell models of Gaucher disease.

Funder

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2017/CP/C6CP07227E

Reference38 articles.

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3. Membrane Domain Formation, Interdigitation, and Morphological Alterations Induced by the Very Long Chain Asymmetric C24:1 Ceramide

4. Reorganization of lipid domain distribution in giant unilamellar vesicles upon immobilization with different membrane tethers

5. Ceramide-Domain Formation and Collapse in Lipid Rafts: Membrane Reorganization by an Apoptotic Lipid

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