In situ condensation of an anti-cancer drug into fibrin gel enabling effective inhibition of tumor cell growth-Reference-Cited by-同舟云学术

In situ condensation of an anti-cancer drug into fibrin gel enabling effective inhibition of tumor cell growth

Published:2019 Issue:78 Volume:55 Page:11679-11682
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Kuwahara Masayasu¹²³⁴^ORCID,Fujita Hiroto¹²³⁴,Kataoka Yuka¹²³⁴,Nakajima Yasuyo⁵⁶⁷⁸⁹^ORCID,Yamada Masanobu⁵⁶⁷⁸⁹,Sugimoto Naoki¹⁰¹¹¹²⁴¹³^ORCID

Affiliation:

1. Graduate School of Integrated Basic Sciences

2. Nihon University

3. Tokyo 156-8550

4. Japan

5. Department of Internal Medicine

6. Division of Endocrinology and Metabolism

7. Graduate School of Medicine

8. Gunma University

9. Maebashi

10. Frontier Institute for Biomolecular Engineering Research (FIBER)

11. Konan University

12. Kobe

13. Graduate School of Frontiers of Innovative Research in Science and Technology (FIRST)

Abstract

Efficient anti-cancer drug condensation enabled equally inhibiting cell proliferation even at a concentration of 7.6 ± 0.36 nM, which was approximately 170-fold lower than the standard therapeutic concentrations of camptothecin (CPT) drugs.

Funder

Japan Agency for Medical Research and Development

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C9CC06418D

Reference44 articles.

1. Platelets and cancer: a casual or causal relationship: revisited

2. The multifaceted role of fibrinogen in tissue injury and inflammation

3. Factor XIIIA—expressing inflammatory monocytes promote lung squamous cancer through fibrin cross-linking

4. Soft fibrin gels promote selection and growth of tumorigenic cells

5. Discovery of an uncovered region in fibrin clots and its clinical significance

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