Spatial and temporal control of drug release through pH and alternating magnetic field induced breakage of Schiff base bonds

Author:

Dunn Alexander E.12345,Dunn Douglas J.12345,Macmillan Alexander6734,Whan Renee6734,Stait-Gardner Tim891011,Price William S.891011,Lim May1234,Boyer Cyrille5234

Affiliation:

1. ARC Centre of Excellence for Functional Nanomaterials

2. School of Chemical Engineering

3. The University of New South Wales

4. Sydney, Australia

5. Australian Centre for NanoMedicine and Centre for Advanced Macromolecular Design

6. Biomedical Imaging Facility

7. Mark Wainwright Analytical Centre

8. Nanoscale Organisation and Dynamics Group

9. School of Science and Health

10. University of Western Sydney

11. Penrith, Australia

Abstract

A novel theranostic controlled drug delivery platform that binds the drug to the nanocarrier by utilising Schiff base bonds to achieve high spatial and temporal control over drug release.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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