One-pot synthesis of 2-naphthols from nitrones and MBH adducts via decarboxylative N

One-pot synthesis of 2-naphthols from nitrones and MBH adducts via decarboxylative N–O bond cleavage

Published:2018 Issue:22 Volume:5 Page:3210-3218
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Han Sang Hoon¹²³⁴,Pandey Ashok Kumar¹²³⁴,Lee Heeyoung¹²³⁴,Kim Saegun¹²³⁴,Kang Dahye⁵⁶⁷⁴,Jung Young Hoon¹²³⁴,Kim Hyung Sik¹²³⁴,Hong Sungwoo⁸⁹⁷⁴⁵^ORCID,Kim In Su¹²³⁴^ORCID

Affiliation:

1. School of Pharmacy

2. Sungkyunkwan University

3. Suwon 16419

4. Republic of Korea

5. Department of Chemistry

6. Korea Advanced Institute of Science and Technology (KAIST)

7. Daejeon 34141

8. Center for Catalytic Hydrocarbon Functionalizations

9. Institute for Basic Science (IBS)

Abstract

The unprecedented one-pot synthesis of 2-naphthols through an acid-mediated decarboxylative N–O bond cleavage of bridged benzoxazepine intermediates is described.

Funder

National Research Foundation of Korea

Institute for Basic Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/QO/C8QO00988K

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