Studies of the stability, nucleophilic substitution reactions, DNA/BSA interactions, cytotoxic activity, DFT and molecular docking of some tetra- and penta-coordinated gold(iii) complexes

Author:

Radisavljević Snežana12345,Đeković Kesić Ana6785,Ćoćić Dušan12345ORCID,Puchta Ralph910111213,Senft Laura910111213ORCID,Milutinović Milena141545,Milivojević Nevena141545ORCID,Petrović Biljana12345ORCID

Affiliation:

1. University of Kragujevac

2. Faculty of Science

3. Department of Chemistry

4. 34000 Kragujevac

5. Serbia

6. State University of Novi Pazar

7. Department of Chemical-Technological Sciences

8. 36200 Novi Pazar

9. Inorganic Chemistry

10. Department of Chemistry and Pharmacy

11. University of Erlangen-Nuremberg

12. Erlangen

13. Germany

14. University of Kragujevac, Faculty of Science

15. Department of Biology

Abstract

The stability in water and at pH = 7.2, substitution reactions with Tu, 5’-GMP, GSH and l-Met, DNA/BSA interactions, cytotoxicity, DFT and molecular docking of gold(iii) complexes with phenanthroline derivatives as inert ligands were studied.

Funder

Ministarstvo Prosvete, Nauke i Tehnološkog Razvoja

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

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