New strong extrafunctionalizable tris(3,4-HP) and bis(3,4-HP) metal sequestering agents: synthesis, solution and in vivo metal chelation-Reference-Cited by-同舟云学术

New strong extrafunctionalizable tris(3,4-HP) and bis(3,4-HP) metal sequestering agents: synthesis, solution and in vivo metal chelation

Published:2019 Issue:43 Volume:48 Page:16167-16183
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Nurchi Valeria M.¹²³⁴⁵^ORCID,Cappai Rosita¹²³⁴⁵^ORCID,Chand Karam⁶⁷⁸⁹¹⁰^ORCID,Chaves Sílvia⁶⁷⁸⁹¹⁰^ORCID,Gano Lurdes¹¹⁷⁸⁹¹⁰^ORCID,Crisponi Guido¹²³⁴⁵^ORCID,Peana Massimiliano¹²¹³¹⁴⁵^ORCID,Zoroddu M. Antonietta¹²¹³¹⁴⁵^ORCID,Santos M. Amélia⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. Dipartimento di Scienze della Vita e dell'Ambiente

2. Università di Cagliari

3. Cittadella Universitaria

4. Monserrato-Cagliari

5. Italy

6. Centro de Quimica Estrutural

7. Instituto Superior Tecnico

8. Universidade de Lisboa

9. Lisboa

10. Portugal

11. Centro de Ciencias e Tecnologias Nucleares(C2TN)

12. Dipartimento di Chimica e Farmacia

13. Università di Sassari

14. Sassari

Abstract

New polydentate 3-hydroxy-4-pyridinones: strong chelators for Fe and Al, excellent in vivo metal sequestration and excretion profiles; extrafunctionalizable for biotargeting purposes.

Funder

Fundação para a Ciência e a Tecnologia

Regione Autonoma della Sardegna

Università degli Studi di Cagliari

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/DT/C9DT02905B

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