Orthogonal nanoarchitectonics of M13 phage for receptor targeted anticancer photodynamic therapy

Author:

Ulfo Luca1ORCID,Cantelli Andrea2,Petrosino Annapaola1ORCID,Costantini Paolo Emidio1ORCID,Nigro Michela1,Starinieri Francesco1,Turrini Eleonora3ORCID,Zadran Suleman Khan1,Zuccheri Giampaolo1,Saporetti Roberto2ORCID,Di Giosia Matteo2ORCID,Danielli Alberto1,Calvaresi Matteo2ORCID

Affiliation:

1. Dipartimento di Farmacia e Biotecnologie, Alma Mater Studiorum – Università di Bologna, via Francesco Selmi 3, 40126 Bologna, Italy

2. Dipartimento di Chimica “Giacomo Ciamician”, Alma Mater Studiorum – Università di Bologna, Via Francesco Selmi 2, 40126 Bologna, Italy

3. Dipartimento di Scienze per la Qualità della Vita, Alma Mater Studiorum—Università di Bologna, Corso d'Augusto 237, 47921 Rimini, Italy

Abstract

Not all viruses are bad. We developed an orthogonal approach (genetic/chemical) to engineer M13 bacteriophages as targeted vectors for efficient photodynamic killing of cancer cells.

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

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