A novel application of hectorite nanoclay for preparation of colorectal cancer spheroids with malignant potential-Reference-Cited by-同舟云学术

A novel application of hectorite nanoclay for preparation of colorectal cancer spheroids with malignant potential

Published:2023 Issue:4 Volume:23 Page:609-623
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Hirade Yoshihiro¹^ORCID,Kubota Munehiro²,Kitae Kaori¹,Yamamoto Harumi¹,Omori Hiroko³,Shinoki Susumu²,Ohmura Takao⁴,Tsujikawa Kazutake¹

Affiliation:

1. Graduate School of Pharmaceutical Science, Osaka University, 1-6 Yamada-oka, Suita City, Osaka 565-0871, Japan

2. Iwaki Laboratory, Kunimine Industries Co, Ltd, 23-5 Kuidesaku, Shimofunao, Iwaki, Fukushima 972-8312, Japan

3. Core Instrumentation Facility, Research Institute for Microbial Diseases, Osaka University, 3-1 Yamada-oka, Suita City, Osaka 565-0871, Japan

4. Kunimine Industries Co, Ltd, 23-5 Kuidesaku, Shimofunao, Iwaki, Fukushima 972-8312, Japan

Abstract

A novel culture system where cancer cells are grown in the presence of nanoclay in adherent plates allows preparation of malignant and dispersed spheroids compared with those formed under ultralow-adherent conditions.

Funder

Japan Agency for Medical Research and Development

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/LC/D2LC00750A

Reference49 articles.

1. In vitro three-dimensional (3D) models in cancer research: An update

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3. The third dimension bridges the gap between cell culture and live tissue

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5. Three-dimensional culture models of normal and malignant breast epithelial cells

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