Synthesis, cytotoxic activity and drug combination study of tertiary amine derivatives of 2′,4′-dihydroxyl-6′-methoxyl-3′,5′-dimethylchalcone-Reference-Cited by-同舟云学术

Synthesis, cytotoxic activity and drug combination study of tertiary amine derivatives of 2′,4′-dihydroxyl-6′-methoxyl-3′,5′-dimethylchalcone

Author:

Wang Chen¹²³⁴⁵,Wu Ping¹²³⁴⁵,Shen Xiao-Ling⁶⁷⁸⁹⁵,Wei Xiao-Yi¹²³⁴⁵,Jiang Zi-Hua¹⁰¹¹¹²¹³^ORCID

Affiliation:

1. Key Laboratory of Plant Resources Conservation and Sustainable Utilization

2. South China Botanical Garden

3. Chinese Academy of Sciences

4. Guangzhou 510650

5. People's Republic of China

6. Laboratory of Herbal Drug Discovery

7. Tropical Medicine Institute

8. Guangzhou University of Chinese Medicine

9. Guangzhou 510405

10. Department of Chemistry

11. Lakehead University

12. Thunder Bay

13. Canada

Abstract

Tertiary amine derivative of DMC (2b) exhibited broad spectrum of cytotoxicity and strong synergism with Taxol® against HeLa/Tax cells.

Funder

National Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

Reference42 articles.

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