Ligand-free Pd/Ag-mediated dehydrogenative alkynylation of imidazole derivatives
Author:
Affiliation:
1. Dipartimento di Chimica e Chimica Industriale
2. Università di Pisa
3. 56124 Pisa
4. Italy
5. Chemistry Research and Drug Design
6. Chiesi Farmaceutici S.p.A.
7. Centro Ricerche
8. 43122 Parma
Abstract
The regioselective synthesis of 2-alkynyl(benz)imidazoles was successfully achieved by Pd(ii)/Ag(i)-mediated dehydrogenative alkynylation of the corresponding (benz)imidazoles with terminal alkynes in an open vessel.
Funder
Chiesi Farmaceutici
Università di Pisa
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA05303E
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