Anti-proliferative, -migratory and -clonogenic effects of long-lasting nitric oxide release in HepG2 cells-Reference-Cited by-同舟云学术

Anti-proliferative, -migratory and -clonogenic effects of long-lasting nitric oxide release in HepG2 cells

Published:2024 Issue:26 Volume:60 Page:3527-3530
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Bormon Rakhi¹,Srivastava Ekta²,Ali Rafat¹^ORCID,Singh Prerna²,Kumar Ashok²³⁴⁵⁶^ORCID,Verma Sandeep¹³⁴⁵⁶^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208016, UP, India

2. Department of Biological Sciences & Bioengineering, Indian Institute of Technology Kanpur, Kanpur 208016, UP, India

3. Centre for Environmental Science and Engineering, Indian Institute of Technology Kanpur, Kanpur-208016, UP, India

4. Centre for Nanoscience, Indian Institute of Technology Kanpur, Kanpur-208016, UP, India

5. Mehta Family Centre for Engineering in Medicine, Indian Institute of Technology Kanpur, Kanpur-208016, UP, India

6. Gangwal School of Medical Sciences and Technology, Indian Institute of Technology Kanpur, Kanpur-208016, UP, India

Abstract

We have synthesized 6,9-disubstituted purines that exhibit sustained release of nitric oxide in the presence of glutathione, displaying significant anticancer properties in HepG2 cells.

Funder

Indian National Academy of Engineering

Department of Science and Technology, Ministry of Science and Technology, India

Science and Engineering Research Board

Ministry of Education, India

Indian Institute of Technology Kanpur

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CC/D4CC00232F

Reference31 articles.

1. Protein Phosphorylation in Cancer: Role of Nitric Oxide Signaling Pathway

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