Detecting early stage structural changes in wild type, pathogenic and non-pathogenic prion variants using Markov state model
Author:
Affiliation:
1. High Performance Computing-Medical & Bioinformatics Applications Group
2. Centre for Development of Advanced Computing (C-DAC)
3. Savitribai Phule Pune University Campus
4. Pune 411007
5. India
Abstract
Markov state model to find out the differences between WT, E200K and E219K systems.
Funder
Ministry of Electronics and Information technology
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2019/RA/C9RA01507H
Reference81 articles.
1. Transmissible Spongiform Encephalopathies
2. SCRAPIE PRIONS
3. Physiology of the Prion Protein
4. Prions: Protein Aggregation and Infectious Diseases
5. Scrapie in sheep
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