Development of a HPLC-DAD stability-indicating method and compatibility study of azathioprine and folic acid as a prerequisite for a monolayer fixed-dose combination-Reference-Cited by-同舟云学术

Development of a HPLC-DAD stability-indicating method and compatibility study of azathioprine and folic acid as a prerequisite for a monolayer fixed-dose combination

Published:2021 Issue:11 Volume:13 Page:1422-1431
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Brusač Edvin¹²³^ORCID,Jeličić Mario-Livio¹²³^ORCID,Amidžić Klarić Daniela¹²³^ORCID,Nigović Biljana¹²³^ORCID,Keser Sabina¹²³,Mornar Ana¹²³^ORCID

Affiliation:

1. University of Zagreb Faculty of Pharmacy of Biochemistry

2. 10000 Zagreb

3. Croatia

Abstract

Physicochemical compatibility of active substances confirmed using multiple techniques and a stability-indicating method developed for quality assessment and in-process control.

Funder

Hrvatska Zaklada za Znanost

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AY/D1AY00294E

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3. Rationale and strategies for formulation development of oral fixed dose combination drug products

4. World Health Organization , Guidelines for registration of fixed-dose combination medicinal products , 2005 , https://www.who.int/medicines/areas/quality_safety/quality_assurance/GuidelinesRegistrationFixedDoseCombinationTRS929Annex5.pdf

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