Synthesis of the extracellular domain of GLP-1R by chemical and biotechnological approaches-Reference-Cited by-同舟云学术

Synthesis of the extracellular domain of GLP-1R by chemical and biotechnological approaches

Published:2022 Issue:37 Volume:12 Page:24278-24287
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Szolomajer János¹^ORCID,Stráner Pál²³,Kele Zoltán¹,Tóth Gábor K.¹⁴,Perczel András²³

Affiliation:

1. Department of Medical Chemistry, Albert Szent-Györgyi Medical School, University of Szeged, H-6720 Szeged, Hungary

2. MTA-ELTE Protein Model. Res. Group and Laboratory of Structural Chemistry and Biology, Pázmány P. stny. 1/A, 1117 Budapest, Hungary

3. Laboratory of Structural Chemistry and Biology, Institute of Chemistry, ELTE Eötvös Loránd University, Pázmány P. stny. 1/A, 1117 Budapest, Hungary

4. MTA-SZTE Biomimetic Research Group, University of Szeged, H-6720 Szeged, Hungary

Abstract

A 10–15 kDa, 3-disulfide-bridges containing protein domain is obtained by SPPS and is expressed in E. coli.

Funder

Emberi Eroforrások Minisztériuma

European Regional Development Fund

Nemzeti Kutatási Fejlesztési és Innovációs Hivatal

Magyar Tudományos Akadémia

Eötvös Loránd Tudományegyetem

Innovációs és Technológiai Minisztérium

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/RA/D2RA02784D

Reference24 articles.

1. GLP‐1 receptor activated insulin secretion from pancreatic β‐cells: mechanism and glucose dependence

2. Bacterial expression and/or solid phase peptide synthesis of 20-40 amino acid long polypeptides and miniproteins, the case study of Class B GPCR ligands

3. Cost-Effective Flow Peptide Synthesis: Metamorphosis of HPLC

4. Structural Insights into the Trp-Cage Folding Intermediate Formation