Fe<sup>III</sup>/TBHP mediated remote C–O bond construction of 8-aminoquinolines: access to methoxylation and cyanomethoxylation-Reference-Cited by-同舟云学术

Fe^III/TBHP mediated remote C–O bond construction of 8-aminoquinolines: access to methoxylation and cyanomethoxylation

Published:2022 Issue:15 Volume:9 Page:4063-4069
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhao Mengfei¹,Zhang Kaixin¹,Xu Jianxiong¹,Li Jizhen¹²^ORCID

Affiliation:

1. Department of Organic Chemistry, College of Chemistry, Jilin University, 2519 Jiefang Road, Changchun 130021, P. R. China

2. State Key laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P.R. China

Abstract

The C5 regioselective methoxylation and cyanomethoxylation of 8-aminoquinolines were achieved under FeIII/TBHP system by tuning the temperature and solvent. TBHP was investigated as an “oxygen” source in the ether bond formation for the first time.

Funder

State Key Laboratory of Rare Earth Resources Utilization

Data Center of Management Science, National Natural Science Foundation of China - Peking University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/QO/D2QO00438K

Reference51 articles.

1. A Bioinspired Catalytic Aerobic Functionalization of Phenols: Regioselective Construction of Aromatic C–N and C–O Bonds

2. Intramolecular Hydrogen Bonding in Medicinal Chemistry