Enhanced basepair dynamics pre-disposes protein-assisted flips of key bases in DNA strand separation during transcription initiation
Author:
Affiliation:
1. Division of Structural Biology and Bioinformatics
2. CSIR-Indian Institute of Chemical Biology
3. Kolkata 700032
4. India
5. Department of Biophysics
6. Bose Institute
7. Kolkata 700054
Abstract
Localized separation of strands of duplex DNA is a necessary step in many DNA-dependent processes, including transcription and replication.
Funder
Department of Science and Technology, Ministry of Science and Technology
Council of Scientific and Industrial Research
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2018/CP/C8CP01119B
Reference49 articles.
1. Initial Events in Bacterial Transcription Initiation
2. Predicting DNA duplex stability from the base sequence.
3. Dissociation kinetics of 19 base paired oligonucleotide-DNA duplexes containing different single mismatched base pairs
4. Crystal Structures of the E. coli Transcription Initiation Complexes with a Complete Bubble
5. Structural Basis of Transcription Initiation
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1. Mathematical Modeling of Transcription Bubble Behavior in the pPF1 Plasmid and its Modified Versions: The Link between the Plasmid Energy Profile and the Direction of Transcription;Biophysics;2021-03
2. Asymmetric base-pair opening drives helicase unwinding dynamics;Proceedings of the National Academy of Sciences;2019-10-18
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