Real-time release monitoring for water content and mean particle size of granules in lab-sized fluid-bed granulator by near-infrared spectroscopy-Reference-Cited by-同舟云学术

Real-time release monitoring for water content and mean particle size of granules in lab-sized fluid-bed granulator by near-infrared spectroscopy

Published:2014 Issue:34 Volume:4 Page:17461-17468
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Otsuka Makoto¹²³⁴,Koyama Akira¹²³⁴,Hattori Yusuke¹²³⁴

Affiliation:

1. Research Institute of Pharmaceutical Sciences

2. Faculty of Pharmacy

3. Musashino University

4. Nishi-Tokyo, Japan

Abstract

Simultaneous real-time monitoring of water content and mean particle size in the powder bed of a fluidized-bed granulator was performed by near-infrared (NIR) spectroscopy through a window, and the findings were used to evaluate the granular properties.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C3RA45375H

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