Regulatory effect of β-glucan secreted by Rhizobium pusense on triglyceride metabolism and their relationships with the modulation of intestinal microbiota in mice fed a high-fat diet

Author:

Zhang Bin1,Zhao Wei2ORCID,Song Dong3,Lyu Xiaomei4ORCID

Affiliation:

1. College of Food Science and Technology, Guangdong Ocean University, Zhanjiang, Guangdong 524088, People's Republic of China

2. State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, People's Republic of China

3. Jiangxi Baiyue Food Co. Ltd, Pingxiang, Jiangxi 337000, People's Republic of China

4. School of Food Science and Technology, Jiangnan University, No. 1800 Lihu Road, Wuxi, Jiangsu 214122, People's Republic of China

Abstract

β-Glucan could activate the hepatic AMPK signaling pathway by regulating the gut microbiota and metabolites through gut–liver crosstalk, exerting a lipid-lowering effect in mice fed a high-fat diet and improving obesity.

Funder

National Basic Research Program of China

National Natural Science Foundation of China

Jiangsu Provincial Key Research and Development Program

Publisher

Royal Society of Chemistry (RSC)

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