Each side chain of cyclosporin A is not essential for high passive permeability across lipid bilayers-Reference-Cited by-同舟云学术

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Each side chain of cyclosporin A is not essential for high passive permeability across lipid bilayers

Published:2023 Issue:12 Volume:13 Page:8394-8397
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ono Takahiro¹^ORCID,Tabata Kazuhito V.²^ORCID,Noji Hiroyuki²³^ORCID,Morimoto Jumpei¹^ORCID,Sando Shinsuke¹³^ORCID

Affiliation:

1. Department of Chemistry & Biotechnology, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan

2. Department of Applied Chemistry, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan

3. Department of Bioengineering, Graduate School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan

Abstract

Cyclosporin A showed lipid bilayer permeability even after the deletion of a side chain.

Funder

Precursory Research for Embryonic Science and Technology

Core Research for Evolutional Science and Technology

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D3RA01358H

Reference20 articles.

1. Cyclic peptide therapeutics: past, present and future

2. Orally Absorbed Cyclic Peptides

3. Macrocyclic Peptides as Drug Candidates: Recent Progress and Remaining Challenges

4. Cyclic Peptides as Drugs for Intracellular Targets: The Next Frontier in Peptide Therapeutic Development

5. Cyclosporin Structure and Permeability: From A to Z and Beyond

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Development and Application of Methodologies for Measuring Passive Membrane Permeability of Peptides toward Understanding the Structure-permeability Relationship of Cyclic Peptides;Journal of Synthetic Organic Chemistry, Japan;2024-06-01

2. Controlling the Chameleonic Behavior and Membrane Permeability of Cyclosporine Derivatives via Backbone and Side Chain Modifications;Journal of Medicinal Chemistry;2023-09-18

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