The heterogeneous crystallization of a novel solvate of clozapine base in the presence of excipients-Reference-Cited by-同舟云学术

The heterogeneous crystallization of a novel solvate of clozapine base in the presence of excipients

Published:2018 Issue:31 Volume:20 Page:4370-4382
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Verma Vivek¹²³⁴⁵,Bannigan Pauric¹²³⁴⁵,Lusi Matteo¹²³⁴⁵^ORCID,Crowley Clare M.¹²³⁴⁵^ORCID,Hudson Sarah¹²³⁴⁵,Hodnett Benjamin K.¹²³⁴⁵,Davern Peter¹²³⁴⁵^ORCID

Affiliation:

1. Synthesis and Solid State Pharmaceutical Centre

2. Department of Chemical Sciences

3. and The Bernal Institute

4. University of Limerick

5. Limerick

Abstract

This paper reports the heterogeneous crystallization of a novel solvate of clozapine base in the presence of excipients.

Funder

Science Foundation Ireland

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/CE/C8CE00663F

Reference47 articles.

1. Crystal engineered albendazole with improved dissolution and material attributes

2. Modification of Crystal Habit and Its Role in Dosage Form Performance

3. The spray drying of acetazolamide as method to modify crystal properties and to improve compression behaviour

4. Habit modification of potassium acid phthalate (KAP) single crystals by impurities

5. The influence of additives on the crystal habit of gibbsite

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